Principles Of Reirradiation

Reirradiation is a highly individualised treatment that is being increasingly used for selected patients. An expert group in reirradiation treatment have highlighted some considerations prior to reirradiation that are common across all anatomical sites. These include:

• Appropriate selection of patients
• The need for appropriate investigations prior to reirradiation
• An approach to account for the previous dose delivered
• Consideration of the original radiotherapy dose distribution, the reirradiation dose and dose constraints
• Choice of radiotherapy technique.

The aim of this document is to provide general principles on clinical considerations for clinical oncologists contemplating reirradiation. It provides links to tumour-site-specific guidance where available.